Health

Scientists got 9 women to try an on-demand contraceptive pill just before sex to prevent pregnancy, and they say it works

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An on-demand birth control pill could soon be a reality.

According to preliminary research published today in the journal BMJ Sexual & Reproductive Health, a pill that combines two existing medications has the potential to prevent pregnancy if a person takes it right before sex.

In a small study of nine women who were ovulating, scientists gave each a pill that contained ulipristal acetate and meloxicam. Ulipristal acetate is the active drug in prescription emergency contraception. Meloxicam is an non-steroidal anti-inflammatory drug (NSAID) that can reduce pain and swelling. It's commonly found in over-the counter pain relievers like ibuprofen, but researchers have also found it can disrupt a person's ovulation cycle.

Research suggests a person has a greater chance of conceiving while ovulating, so the researchers wanted to see if this drug combination could work during that particular phase of the menstrual cycle. To do that, the researchers gave women between 18 and 35, who were considered healthy with normal menstrual cycles, the pill they were testing.

They found six of the nine women they studied experienced ovulation disruption, and 8 of the women met the criteria for incomplete ovulation, meaning an egg didn't drop from their ovaries into their uterus, so they can't become pregnant.

According to the researchers, their findings suggest this new pill is the best-known medication for stopping successful ovulation, but more extensive studies and safety tests should be done.

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Julia Naftulin
Julia Naftulin is an editor on Business Insider's Special Projects team, where she leads editorial initiatives spanning the business, tech, and lifestyle spaces.She has launched and managed series covering how companies adopt and implement AIthe business of food, the 2026 World Cup, and innovation in supply chain management, as well as projects like the AI Power List.Previously, Julia served a five-year tenure as health reporter at Business Insider, covering general wellness and the intersection of relationships, psychology, and culture.Julia reported on the life of a Wall Street accountant-turned-professional-girlfriend, took readers inside Goop's first cruise, explored the dating industry, and delved into the latest plastic surgery trends. She was also Business Insider's resident relationship advice columnist, penning the now-defunct column Doing It Right.She has held editor roles at Health.com and Dotdash Meredith. Her work has been published in Health magazine and on Time, Apartment Therapy, The Knot, and Bicycling.com.Julia graduated from Syracuse University with a Bachelor of Science in Magazine Journalism. Julia lives in Philadelphia with her dachshund, Gretchen.